P R O F. D R. K L A U S J. P A L M E
| Last Name, Name PALME, Klaus | Position Title University Professor, Institute of Biology II, University of Freiburg |
EDUCATION/TRAINING
| Institution and Location | Degree | Field of Study |
| University of Freiburg University of Ulm | Diploma Dr. rer. nat. | Chemistry Biochemistry |
A. Positions and Honors
Employment/Experience
1982-1983 Research Fellow, Salk Institute for Biological Studies, San Diego, USA
1984-1985 Research Fellow University of Cologne
1986-1995 Senior scientist and group leader, MPI for Plant Breeding, Cologne
1995-2001 Professor and Head of an Independent Research Group, Max-Delbrück-Laboratorium, Cologne
2000-2001 Professor, Swedish University of Agricultural Sciences, Umea, Sweden
2001-present Professor, Institute for Biology II / Botany, University Freiburg
2005-present Board of Directors, Freiburg Center of Systems Biology
2008-present Principle Investigator, BIOSS Center for Biological Signalling Studies
2010-2014 Executive Director, Institute of Biology
Honors, Awards and Scholarships
1974-1977 Scholarship, German National Merit Foundation
1993 Academia Europaea (UK, elected fellow)
1995 G-Prize (Intospace, Paris)
2000 European Molecular Biology Organisation (EMBO, elected fellow)
2002 Max-Planck-Research Award
2006 DAGM Award
2008-present Guest Professor, Institute of Genetics and Developmental Biology. Chinese Academy of Sciences, Bejing, PRC
2008-2012 Freiburg Institute of Advanced Studies, Fellow
2013-present Honorary Professor, Jinan University (China)
2013-present Guest Professor, North-West A&F University (China)
2015 Academia das Ciências de Lisboa (Portugal, elected fellow)
2017-present Guest Professor, School of Biological Science and Technology Shandong Agricultural University, PRC
Editorial/Advisory Board (´til 2015)
Plant Biosystems, Plant Cell Physiology; The Plant Journal, Int. J. Plant Sciences, J. Integ. Plant Biol., Molecular Plant; New Negatives Plant Sciences, Journal of Bioinformatics, Computational and Systems Biology
Editor / Editorial Board (2015-2020): J. Plant Science & Molecular Breeding, Microbiology and Genetics, Springer.
Board of Trustees
BioImaging Center LMU, Munich
Board of Trustees
Helmut und Elisabeth Uhl Stiftung
Founder ScreenSYS GmbH
| 2015-2018 | | German Space Agency (DLR) German Ministry of Economy (BMWi) Initiator and Coordinator Integrative systems analysis of microgravity on growth of Arabidopsis thaliana |
| 2015-2018 | | German Research Council (DFG), Collaborative Research Center (SFB) “Functional specificity by coupling and modification of proteins” Principle Investigator Functional specificity of protein interaction networks in plant hormone dependent regulation of cell fate determination |
| 2012 – 2016 | | Academic-Industrial Research Consortium, German Ministry of Research and Technology (BMBF, “eBIO – Innovation for Systems Biology”), Germany Founder, Coordinator and Principle Investigator “BioSystems Analysis or reprogramming to improve industrial plant embryo production” |
| 2012 – 2015 | | German Academic Exchange Service (DAAD) “Plant Bio Goes India”, India & Germany Initiator and Coordinator Exchange and Teaching Program for Master and Graduate Students between University of Freiburg, Germany, and the National Institute of Science Education and Research, Bhubaneswar, India |
| 2010-2013 | | German Space Agency (DLR) German Ministry of Economy (BMWi) Initiator and Coordinator Analysis of gravity signalling mechanisms in Arabidopsis thaliana |
| 2009 – 2015 | | German Research Council (DFG) Priority Programme, Germany Co-founder and Principle Investigator “Information- and Communication Theory in Molecular Biology (InKoMiBo)” |
| 2009 – 2012 | | Academic-Industrial Research Consortium, German Ministry of Research and Technology (BMBF, “Development of Innovative Methods for Systems Biology”), Germany Founder, Coordinator and Principle Investigator “Quantitative 3D and 4D cell analysis in living organisms - novel instrumentation, computational tools and proof of concept applications” |
| 2009 – 2012 | | Academic-Industrial Research Consortium, German Ministry of Research and Technology (BMBF, “Systems Biology Program”), Germany Co-founder, Coordinator and Principle Investigator “Systems biology approach to cellular reprogramming in Brassicaceae cells” |
| 2009 – 2012 | | Academic-Industrial Research Consortium, German Ministry of Research and Technology (BMBF, “Optical Technology Development”), Germany Co-founder and Principle Investigator “3-D Analysis of Living Cells in Tissues” |
| 2009 – present | | Chinese-German Joint Group for Plant Hormone Research, China & Germany Co-founder and Principle Investigator Participating institutions include Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China and Faculty of Biology and Faculty of Biology, University of Freiburg, Germany |
| 2007 – present | | Centre for Biological Signalling Studies (BIOSS), Germany Co-founder, Principle Investigator |
| 2007 – present | | German Research Council (DFG), Collaborative Research Center (SFB) on “Functional Coupling and Modification of Proteins”, Germany Principle Investigator |
| 2005 – present | | Centre for Biosystems Analysis (ZBSA), Germany Co-founder, Board of Directors |
| 2008 – 2010 | | Finish-German Signalling Network (co-funded by Finish Academy of Sciences and German Research Council), Finland & Germany Co-founder and Principle Investigator |
| 2007 – 2012 | | European Framework Programme (FP7-KBBE-2007, “ENERGY PLANTS - Novel plants for energy production”), European Union Co-founder and Principle Investigator “Enhancing Poplar Traits for Energy Applications” |
| 2005 – 2010 | | German Research Council funded Graduate School (GRK 1305) “Signal Systems in Plant Model Organisms” Initiator and Study Dean |
| 2002 – 2012 | | Collaborative Research Centre on “Signal Mechanisms in Embryogenesis and Principle Investigator |
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| CITATION METRICS |
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Thomson Reuters Web of Science 2017 |
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| 20 HIGHLY CITED PUBLICATIONS (selected) |
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| Bevan, M., et al. (1998) Sequence of a contiguous 1.9.Mb region from chromosome 4 of Arabidopsis thaliana. Nature 319, 485-488. |
| Gälweiler, L., Guan, C., Müller, A., Wisman, E., Mendgen, K., Palme, K. (1998) Regulation of polar auxin transport by AtPIN1 in Arabidopsis vascular tissue. Science 282, 2226-2230. |
| Geldner, N., Friml, J., Stierhof, S., Jürgens, G., Palme, K. (2001) Reversible regulation of polar insertion of AtPIN1. Nature 413, 425-428. |
| Friml, J., Wisniewska, J., Benková, E., Mendgen, K., Palme, K. (2002) Lateral relocalisation of auxin efflux regulator PIN3 mediates tropic growth responses in Arabidopsis. Nature 415, 806-809. |
| Blilou, I., Wildwater, M., Willemsen, V., Papanov, I., Friml, J., Heidstra, R., Palme, K., Scheres, B. (2005) The PIN auxin efflux facilitator network controls patterning and cell division in Arabidopsis roots. Nature 433, 39-44. |
| Steinmann, T., Geldner, N., Grebe, M., Mangold, S., Jackson, C., Paris, S., Gälweiler, L., Palme, K., Jürgens, G. (1999) Coordinated polar localization of auxin efflux carrier PIN1 by GNOM ARF GEF. Science 286, 316-318. |
| Müller, A., Guan, C., Gälweiler, L., Tänzler, P., Huijser, P., Marchant, A., Parry, G., Bennett, M., Wisman, E., Palme, K. (1998) AtPIN2 defines a locus of Arabidopsis for root gravitropism. EMBO J. 17, 101-109. |
| Friml, J., Benkova, E., Bilou, I., Wisniewska, J., Hamann, T., Ljung, K., Woody, S., Sandberg, G., Scheres, B., Jürgens, G., Palme, K. (2002). AtPIN4 mediates sink-driven auxin gradients and root patterning in Arabidopsis. Cell 108, 661-673. |
| 20 HIGHLY CITED PUBLICATIONS (selected, cont’d) |
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| Friml, J., Yang, X., Michniewicz, M., Weijers, D., Quint, A., Tietz, O., Benjamins, R., Ouwerkerk, PBF., Ljung, K., Sandberg, G., Hooykaas, PJJ., Palme, K., Offringa, R. (2004) A PINOID-dependent binary switch in apical-basal PIN polar targeting directs auxin efflux. Science 306, 862-865. |
| Swarup, R., Friml, J., Marchant, A., Palme, K., Bennett, M. (2001)Localization of the auxin permease AUX1 suggests two functionally distinct hormone transport pathways operate in the Arabidopsis root apex. Genes & Develop. 15, 2648-2653. |
| Teale, W.D., Paponov, I.A., Palme, K. (2006) Auxin in action: signaling, transport and the control of plant growth. Nature Rev. Mol. Cell Biol. 7, 847 – 859. |
| Molendijk, A.J., Bischoff, F., Rajendrakumar, C.S.V., Friml, J., Braun, M., Gilroy, S., Palme, K. (2001) Polar localization of Rop GTPases in trichoblast budding and regulation of root hair tip growth. EMBO J. 20, 2779-2788. |
| Ottenschläger, I., Wolff P., Wolverton, C., Bhalerao, R., Sandberg, G., Ishikawa, H., Evans, M., Palme, K. (2003) Gravity induced auxin transport from Arabidopsis columella to lateral root cap cells. Proc. Natl. Acad. Sci. USA 100, 2987-2991. |
| Brzobohaty, B., Moore, I., Kristoffersen, P., Bako, L., Campos, N., Schell, J., Palme, K. (1993) A ß-glucosidase that releases active cytokinin is localized in the maize root meristem. Science 262, 1051-1054. |
| Hesse, T., Feldwisch, J., Balshüsemann, D., Bauw, D., Puype, M., Vandekerckhove, J., Löbler, M., Klämbt, D., Schell, J., Palme, K. (1989) Molecular cloning and structural analysis of a gene from Zea mays (L.) coding for a putative receptor for the plant hormone auxin. EMBO J. 8, 2453-2461. |
| Reinemer, P., Prade, L., Hof, P., Neuefeind, T., Huber, R., Zettl, R., Palme, K., Schell, J., Koelln, I., Bartunik, H.D., Bieseler, B. (1996) Three-dimensional structure of glutathione S-transferase from Arabidopsis thaliana at 2.2 A resolution. Structural characterization of herbicide conjugating plant glutathione S-transferases and a new active site architecture. J. Mol. Biol. 255, 289-309. |
| Friml, J., Palme, K. (2002) Auxin transport in plant development old concepts, new questions. Plant Mol. Biol. 49, 273-284. |
| Paponov, I., Teale, W.D., Trebar, M., Blilou, I., Palme, K. (2005) The PIN auxin efflux facilitators: evolutionary and functional perspectives. Trends Plant Sci. 10, 170-177. |
| Reintanz, B., Lehnen, M., Reichelt, M., Gershenzon, J., Kowalczyk, M., Sandberg, G., Godde, M., Uhl, R., Palme, K. (2001) |
| Rück, A., Palme, K., Hesse, F., Venis, M., Napier, R., Felle, H. (1993) Patch clamp analysis establishes a role for ERabp in the control of IAA dependent ion fluxes in Zea mays protoplasts. Plant J. 4, 41-46. |
Short biography
Klaus Palme isolated and characterized the first plant hormone receptor gene, later he discovered and functional analyzed the PIN gene family, thereby making a globally acknowledged breakthrough which has fuelled the analysis of this important plant process for many years and by numerous followers around the world. He opened new important fields in plant biology. Klaus Palme has an excellent track record in excellent research and teaching in both academia and industry as reflected by international recognitions and prizes and foundation of a biotechnology company. Many of his publications are highly cited illustrating the high quality and attractiveness. His work is acknowledged by several prizes, documented by the choice in international scientific organizations, and through the prestigious Humboldt foundation. He has been and is a plenary speaker at and organizer of major national and international conferences in the field of biological signaling, breeding and systems biology.
Publications 2014-2016
Schmidt, T., Dürr, J., Keuper, M., Blein, T., Palme, K., Ronneberger, O. (2014) Variational attenuation correction in Two-View Confocal Microscopy. BMC Informatics 14, 366.
Liu, K., Skibbe, H., Schmidt, T., Blein, T., Palme, K., Brox, T., Ronneberger, O. (2014) Rotation-invariant HOG descriptors using Fourier analysis in polar and spherical coordinates. Int. J. Computer Vision 10, 342-364.
Mai, D., Dürr, J., Palme, K., Ronneberger, O. (2014) Accurate Detection in Volumetric Images Using Elastic Registration Based Validation. Lect. Note Comp. Sci. 8753, 453-463.
Aubry-Hivet, D., Nziengui, H., Rapp, K., Oliveira, O., Paponov, I., Li, Y., Vagt, N., Hauslage, J., Braun, M., Ditengou, F.A., Dovzhenko, A., Palme, K. (2014) Analysis of gene expression during parabolic flights reveals distinct early gravity responses in Arabidopsis root tips. Plant Biology 16, 129-141.
Ruyters, G., Spiero, F, Legue, V., Palme, K. (2014) Plant biology in space. Plant Biol. 16, 1-3.
Schmidt, T., Pasternak, T., Aubry, D., Dovzhenko, A., Teale, W., Burkhardt, H., Ronneberger, O., Palme, K. (2014) The iRoCS Toolbox - 3D analysis of the plant root apical meristem at cellular resolutiont. Plant J. 77, 806-814.
Hosp, J., Ribarits, A., Szaszka, K., Jin, Y., Tashpulatov, A., Baumann, M., Resch, T., Friedmann, C., Ankele, E., Voronin, V., Palme, K., Heberle-Bors, E., Touraev, A. (2014) A tobacco homolog of DCN1 is involved in cellular reprogramming and in developmental transitions. Plant Cell Reports 33, 1187-1202.
Palme, K., Li, X., Teale, W.D. (2014) Towards second green revolution: engineering nitrogen use efficiency. J. Genet. Genomics 41, 315-316.
Ditengou, F.A., Müller, A., Rosenkranz, M., Felten, J., Legué, V., Palme, K., Schnitzler, J.P., Polle, A. (2015a) Volatile signalling by sesquiterpenes from ectomycorrhizal fungi reprograms root architecture. Nature Comm. 6:6279,DOI: 10.1038/ncomms7279.
Wang, H., Xugang Li, X., Krause, L., Görög, M., Schüler, O., Hauslage, J., Hemmersbach, R., Kircher, S., Lasok, H., Haser, T., Rapp, K., Schmidt, J,, Yu, X., Pasternak, T., Aubry-Hivet, D., Tietz, O., Dovzhenko, A., Palme, K., Ditengou, F.A. (2015) 2-D Clinostat for Simulated Microgravity Experiments with Arabidopsis Seedlings. Microgravity Sci. Technol. 28, 59-66.10.1007/s12217-015-9478-1.
Pasternak, T., Tietz, O., Rapp, K., Begheldo, M., Nitschke, R., Ruperti, B., Palme, K. (2015) Protocol: an improved and universal procedure for whole-mount immunolocalization in plants. Plant Methods 11, 50. DOI: 10.1186/s13007-015-0094-2.
Bi, Z., Merl-Pham, J., Uehlein, N., Mühlhans, S., Zimmer, I., Voss, A., Walch, A.K., Kaldenhoff, R., Palme, K., Schnitzler, J.-P., Block, K. (2015) RNAi-mediated down-regulation of plasma membrane intrinsic proteins (PIPs) and its multi-scale effects in poplar: a proteomic and physiological survey. J. Proteomics 128, 321-332.
Zermiani, M., Zonin, E., Nonis, A., Begheldo, M., Pegoraro, M., Vezzaro, A., Baldan, B., Trentin, A., Masi, A., Ceccato, L., Fadanelli, L., Ramina, A., Palme, K., Quintier, L., Benedetto Ruperti, B. (2014) Identification of the Arabidopsis RAM/MOR signalling network: adding new regulatory players in plant stem cell maintenance and cell polarization. Annals Botany 116, 69-89.
Zermiani, Monica; Zonin, Elisabetta; Nonis, Alberto; et al. (2015) Ethylene negatively regulates transcript abundance of ROP-GAP rheostat-encoding genes and affects apoplastic reactive oxygen species homeostasis in epicarps of cold stored apple fruits. J. Exp. Bot. 66, 7255-7270.
Omelyanchuk, N.A., Kovrizhnykh, V.V., Oshchepkova, E.A., Pasternak, T., Palme, K., Mironova, V.V. (2016) A detailed expression map of PIN1 auxin transporter in Arabidopsis thaliana root. BMC Plant Biology 16 Suppl 1 DOI: 10.1186/s12870-015-0685-0.
Schopfer, P., Palme, K. (2016) Inhibition of cell expansion by rapid ABP1-mediated auxin effect on microtubules? A critical comment. Plant Physiology 170, 23-25.
Dalal, J., Lewis, D.R., Tietz, O., Brown, E.M., Brown, C.S., Palme, K., Muday, G.K., Sederoff, H.W. (2016) ROSY1, a novel regulator of gravitropic response is a stigmasterolbinding protein. J. Plant Physiol. 196, 28-40.
Carranza, A.P.S., Singh, A., Steinberger, K., Panigrahi, K., Palme, K., Dovzhenko, A., Dal Bosco (2016) Hydrolases of the ILR1-like family of Arabidopsis thaliana modulate auxin response by regulating auxin homeostasis in the endoplasmic reticulum. Scientific Reports 6, 24212. DOI 10.1038/srep24212.
Meinert, T., Tietz, O., Palme, K., Rohrbach, A. (2016) Separation of ballistic and diffusive fluorescence photons in confocal Light-Sheet Microscopy of Arabidopsis roots. Scientific Reports 6, 30378. DOI 10.1038/srep30378.
Palme, K., Teale, W., Dovzhenko, A. (2016) Plant Signaling: HY5 Synchronizes Resource Supply. Current Biology 26, R328-R329.
Chuprov–Netochin, R., Neskorodov, J., Marusich, E., Mishutkina, Y., Volynchuk, P., Leonov, S., Skryabin, K., Ivashenko, A., Palme, K., Touraev, A. (2015) Novel small molecule modulators of plant growth and development identified by high-content screening with plant pollen. BMC Plant Biology 16, 192. DOI: 10.1186/s12870-016-0875-4.
Johnson, G., Kangas, J., Dovzhenko, A., Trojok, R., Voigt, K., Majarian, T., Palme, K., Murphy, R.F. (2016) A method for characterizing phenotypic changes in highly variable cell populations and its application to high content screening of Arabidopsis thaliana protoplasts. Cytometry A. Vol 91, in press (including journal Feature on this article).
地址：山东省泰安市岱宗大街61号 邮编：271018